Zinc Oxide: Uses, Safety and Practical Tips

Zinc oxide is a simple ingredient you’ve probably used without thinking about it. It’s in sunscreens, diaper creams, and many ointments because it creates a physical barrier on the skin and helps protect irritated areas. That barrier effect makes it handy for everyday skin care and for protecting wounds from moisture and friction.

Common uses and forms

Zinc oxide comes as creams, ointments, pastes, and powders. Low- to mid-strength formulations (often 5–25%) are common in sunscreens and facial products. Thicker pastes and ointments for diaper rash or skin protection can contain 20–40% zinc oxide. In clinics you’ll also see dressings and creams that use zinc oxide to protect fragile skin and reduce friction around wounds.

Typical uses you’ll notice: sunscreen for broad-spectrum protection, barrier creams to prevent chafing or moisture damage, and basic wound-protective ointments for minor cuts and scrapes. People with diabetes often use zinc-oxide-based barrier creams to protect intact skin from moisture and rubbing — but active ulcers need professional care.

How to use zinc oxide safely

Use the right form for the job. Sunscreen with zinc oxide should be applied like any sunscreen: apply generously to dry skin before sun exposure and reapply every two hours or after swimming or heavy sweating. For barrier creams, apply a thin, even layer to clean, dry skin where friction or moisture is a problem.

Don't put thick pastes or powders into deep, open wounds. Those need assessment and treatment by a healthcare provider. If you have diabetes, check wounds daily and seek medical advice for anything that is red, draining, painful, hot, or not improving. Zinc oxide can protect surrounding skin, but it’s not a substitute for wound debridement or a prescribed dressing when those are needed.

Patch-test products if you have sensitive skin: apply a small amount to the inside of your forearm and watch for 24–48 hours. Stop use if you get redness, burning, or blistering. Avoid inhaling powders—zinc oxide in fine powder form can irritate the lungs if breathed in.

Few drug interactions happen with topical zinc oxide, but oral zinc supplements can interact with antibiotics and other medications. Tell your doctor about all supplements and medicines you take.

Store creams in a cool, dry place and discard any product past its expiry date. For babies, use diaper creams as directed and keep the product away from eyes and mouth. If a rash gets worse or you see signs of infection, contact your healthcare provider.

Want help picking the right zinc oxide product? Ask your pharmacist or clinician for a recommendation based on the problem you’re treating—sun protection, moisture barrier, or wound care—and follow their instructions for safe use.